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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK11
All Species:
44.24
Human Site:
Y253
Identified Species:
69.52
UniProt:
Q15831
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15831
NP_000446.1
433
48636
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Chimpanzee
Pan troglodytes
XP_524028
433
48572
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Rhesus Macaque
Macaca mulatta
XP_001093806
433
48511
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Dog
Lupus familis
XP_542206
439
49298
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTK7
436
49248
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Rat
Rattus norvegicus
NP_001101539
436
49227
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519859
324
36639
G157
N
L
L
L
T
T
D
G
T
L
K
I
S
D
L
Chicken
Gallus gallus
Q0GGW5
440
49774
Y253
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Frog
Xenopus laevis
Q91604
432
49054
Y256
Y
N
I
T
T
G
L
Y
P
F
E
G
D
N
I
Zebra Danio
Brachydanio rerio
NP_001017839
440
49807
Y252
Y
N
I
T
T
S
L
Y
P
F
E
G
D
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650302
567
62874
Y376
Y
N
L
A
T
G
Q
Y
P
F
E
G
D
N
I
Honey Bee
Apis mellifera
XP_623596
434
50409
S258
A
N
G
C
E
T
F
S
G
F
K
V
D
I
W
Nematode Worm
Caenorhab. elegans
Q9GN62
617
69630
Y388
Y
N
L
V
S
G
K
Y
P
F
E
K
P
V
L
Sea Urchin
Strong. purpuratus
XP_780778
429
48923
K251
Q
D
V
F
S
G
F
K
V
D
I
W
S
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
L238
Y
A
L
L
C
G
T
L
P
F
D
D
E
N
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
99.3
92.4
N.A.
90.1
90.5
N.A.
57.7
89.3
81.2
82.2
N.A.
41.4
54.6
29.8
57.7
Protein Similarity:
100
99.3
99.5
94.5
N.A.
93.3
93.1
N.A.
63.2
93.1
87.5
87.2
N.A.
54.8
71.8
43.7
72.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
93.3
N.A.
80
20
46.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
100
93.3
N.A.
86.6
26.6
66.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
7
0
0
7
7
7
74
7
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
74
0
7
0
0
% E
% Phe:
0
0
0
7
0
0
14
0
0
87
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
80
0
7
7
0
0
67
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
60
0
0
0
0
0
0
0
7
7
0
7
74
% I
% Lys:
0
0
0
0
0
0
7
7
0
0
14
7
0
0
0
% K
% Leu:
0
7
27
14
0
0
60
7
0
7
0
0
0
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
80
0
0
0
0
0
0
0
0
0
0
0
74
0
% N
% Pro:
0
0
0
0
0
0
0
0
80
0
0
0
7
0
0
% P
% Gln:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
14
7
0
7
0
0
0
0
14
7
0
% S
% Thr:
0
0
0
60
74
14
7
0
7
0
0
0
0
0
0
% T
% Val:
0
0
7
7
0
0
0
0
7
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% W
% Tyr:
80
0
0
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _